European Conference on Interventional Oncology
ECIO countries

April 13-16 | Rotterdam, NL

April 13-16 | Rotterdam, NL

April 13-16 | Rotterdam, NL

April 13-16 | Rotterdam, NL

April 13-16 | Rotterdam, NL

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ProgrammeHonorary Lecture

Honorary Lecture

IO for colorectal liver metastases: the path to clinical excellence

Constantinos T. Sofocleous
Constantinos T. Sofocleous
ECIO 2024 Honorary Lecturer
(New York/US)

About Dr. Sofocleous

Dr. Sofocleous is a professor of interventional radiology at Weill-Cornell Medical College. He has practiced interventional oncology at Memorial Sloan Kettering Cancer Center in New York city since 2002. He is the head of a Memorial Sloan Kettering research lab, “The Sofocleous Lab”, dedicated in the assessment of image-guided interventional oncology treatment assessments for colorectal metastatic disease.

Dr. Sofocleous is a proud fellow of the SIR and CIRSE and he is a global ambassador of IR. His role was pivotal in collaborations between CIRSE and SIR with the establishment of the Global IR summit, the completion of a global IR survey recently presented at SIR and CIRSE 2024 and recently published in JVIR. He has served as the International Counselor and a member of the Executive Council of the Society of Interventional Radiology since 2021 and as a counselor at large and member of the SIR Board of Directors as of April 2025. He is a founding member and served as a board member of the Society of Interventional Oncology from 2017-2023. His role was important for the collaboration between CIRSE and SIO. He was the 2016 WCIO Program Chair.

Dr. Sofocleous serves in the editorial board of CVIR, Cancers, and International Journal of Hyperthermia. He has served as the editor of dedicated issues on interventional oncology for colorectal cancer metastatic disease in Cancers and the International Journal of Hyperthermia. Sofocleous has represented interventional oncology/radiology in the multidisciplinary National Comprehensive Cancer Network Panel for Colorectal, Anal, and Intestinal Cancers since 2009. His work focuses on image-guided treatment of metastatic colorectal disease in the liver and lungs. He has authored or co-authored over 220 peer-reviewed scientific papers, with a Scopus author citation index of 55 and over 13,000 citations. According to Google Scholar, his h-index is 65 with an i10 index of 162 with 19256 citations for his scientific work as of January 2025.

Dr. Sofocleous has consistently supported CIRSE with uninterrupted attendance as a presenter or faculty since 2002. He has delivered over 330 invited lectures in the field of interventional oncology. He has received National Cancer Institute and National Institute of Health grant awards including a 2019 prestigious R01 Clinical Trial Award entitled “Optimizing Thermal Ablation for Colon Cancer Liver Metastases: Rapid Tissue Analysis Allowing for Immediate Retreatment; Metabolic Imaging Biomarker Validation; and Predictive Genetic Signatures”.

He is the lead investigator in several clinical trials of thermal ablation and radioembolization of colorectal hepatic metastases including the multicenter multinational Society of Interventional Oncology sponsored ACCLAIM trial (Ablation with Confirmation of Colorectal Liver Metastases). He is also the primary investigator of an SIR Foundation sponsored trial entitled “Correlations of TAD to Histopathologic Changes, Local Tumor Control and Immune Response after TARE of CLM”. His ongoing work keeps improving image guided therapy for colorectal metastatic disease.

Dr. Sofocleous has been recognized as a Castle Connolly top doctor for over 10 years and featured in New York Magazine as a result of his clinical work.